Daten 2018 (eng)

Data on the laboratory-based surveillance of meningococci (2018)

Introduction

The German National Reference Centre for Meningococci and Haemophilus influenzae (NRZMHi) is assigned by the Robert Koch Institute (RKI) with the performance of laboratory based surveillance of invasive meningococcal disease (IMD). In 2018, 361 samples from 320 individuals were analyzed. The NRZMHi confirmed Neisseria meningitidis in 264 patients, in 235 of them from primarily sterile compartments (latter figure corresponds to the number of cases with invasive disease). In 32 patients (13.6% out of 235) detection of meningococci was carried out using molecular techniques only. During the same period 295 cases of IMD were notified to the RKI (data as of 16.01.2019, SurvStat@RKI). Given that all processed cases of IMD were notified retrospectively, one can assume an 80% coverage of IMD by NRZMHi (82% in 2017).

There were only minor changes of the incidence of IMD in Germany: 0.34/100,000 in 2017 vs. 0.36/100,000 in 2018 (data as of 16.01.2019, SurvStat@RKI).

Frequency of serogroups B, C, W and Y (2011-2018)

The number of serogroup B cases analysed at the NRZMHi continued to decrease in 2018, whereas the number of serogroup W cases increased. The number of serogroup C and Y cases remained stable.

Serogroups according to age groups (2017-2018)

In 2018, the majority of IMD cases irrespective of the serogroup occurred in patients aged 20 years or above.

Serogroups according to federal states (2018)

For seven invasive cases, the serogroup could not be determined (NG).

Geographic distribution of serogroups (2018)

The coloured symbols represent IMD cases with the respective serogroups. Serogroup C dominated in Baden-Wuerttemberg and Y in North Rhine-Westphalia.

All maps were generated with EpiScanGIS.

Most common finetypes (2018)

In 2018, a total of 98 different serogroup-PorA-FetA combinations (finetypes) were identified.

Most common finetypes according to age groups (2018)

Many finetypes predominantly occurred in patients aged 20 years or more.

Geographic distribution of the four most common finetypes (2018)

The yellow circles represent IMD cases with the respective finetype.

All maps were generated with EpiScanGIS.

Antibiotic susceptibility of invasive isolates

The proportions of penicillin intermediate susceptible and penicillin resistant isolates remained almost stable: 21.4% and 4.6%, respectively, in 2017 and 24.0% and 5.1%, respectively, in 2018.

Disclaimer

The above data were generated with federal funds (RKI). Scientific use is prohibited without prior written consent by NRZMHi or RKI. Commercial use is strictly prohibited. Inclusion of figures or tables in talks or oral presentations is not allowed.