Academic career: | | |
1989-1996 | | Studies of Medicine at the Medical School Hannover |
1997-1998 | | AiP at the Institute for Medical Microbiology, University of Mainz |
1999-2002 | | Research Fellow at the Institute for Hygiene and Microbiology Würzburg |
since 2002 | | Group leader at the Institute for Hygiene and Microbiology Würzburg |
2006 | | Specialist for Microbiology, Virology and Infection Epidemiology (Bayerische Landesärztekammer) |
2009 | | Habilitation: „Medical Microbiology“, University of Wuerzburg, mentor: Prof. Dr. M. Frosch |
06/2010-03/2012 | | ‚Akademische Oberrätin auf Zeit’ at the Institute of Hygiene and Microbiology, Wuerzburg |
2011 | | Appointment associate professor (W2) for Medical Microbiology and Immunology at the Institute for Clinical Microbiology and Immunology, University of Erlangen (Prof. Dr. C. Bogdan) (declined) |
04/2012 | | Associate professor (Cellular Microbiology; W2), at the Institute of Hygiene and Microbiology, Wuerzburg |
Major research interests: |
Infection biology, Neisseria meningitidis, bacteria-host cell interaction, interaction of N. meningitidis with cells of the blood-cerebrospinal-fluid barrier, signal transduction, cytoskeletal dynamics and signalling, transcriptional regulators |
Fellowships/Awards: |
2009 | | Becton-Dickinson Scientific Award (German Society for Hygiene and Microbiology) |
Research Topics |
Molecular basis of host-pathogen interaction in meningococcal meningitis |
Project Management |
2002-2005 | | Interaction of Neisseria meningitidis with cells of the human blood brain barrier Schwerpunktprogramm SPP1130 “Infektionen des Endothels” |
2005-2006 | | Pathologische Aktivierung humaner Thrombozyten durch Meningokokken und Gruppe B Streptokokken: Molekulare Mechanismen und klinische Bedeutung (IZKF Würzburg, Projekt A33) |
2007-2009 | | Untersuchungen zur Integrin-vermittelten Signalweiterleitung in Endothelzellen nach Infektion mit N. meningitidis“ (DFG-Normalverfahren, SCHU2394/1-1) |
2010-2013 | | Untersuchungen zur Integrin-vermittelten Signalweiterleitung in Endothelzellen nach Infektion mit N. meningitidis“ (DFG-Normalverfahren, SCHU2394/1-2) |
2014-2015 | | Role of non-receptor tyrosine kinases and activated signaling pathways in bacterial adherence and invasion of host cells (BaCaTec (Bavaria California Technology Center), Förderprojekt Nr. 12 [2013-2]) |
2014-2016 | | Untersuchung zur funktionellen Relevanz von Sphingomyelinasen und Ceramiden in der Pathogenese der Meningokokkeninfektion“ (SCHU 2394/2-1; Teilprojekt P03 im Rahmen der Forschergruppe FOR 2123 „Sphingolipids in infection control“) |
2016-2019 | | Meningococcal ligands and molecular targets required for adhesion and penetration of the blood-cerebrospinal fluid barrier under shear stress (Teilprojekt im Rahmen des GRK2157 3D Tissue Models for Studying Microbial Infections by Human Pathogens) |
2018-2019 | | Blood brain barrier failure during bacterial and viral infections (BaCaTec (Bavaria California Technology Center), Förderprojekt) |
2017-2019 | | Untersuchung zur funktionellen Relevanz von Sphingomyelinasen und Ceramiden in der Pathogenese der Meningokokkeninfektion“ (SCHU 2394/2-2; Teilprojekt P03 im Rahmen der Forschergruppe FOR 2123 „Sphingolipids in infection control“) |
Editorial work: |
Reviews for: Journal of Molecular Microbiology International Journal of Medical Microbiology, Infection and Immunity, Cellular Microbiology, Nature Reviews, Plos Pathogens |
Scientific Reviewer for The Meningitis Research Foundation |